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Some of Dr. Aiken's Publications (Meet Dr. Nanci Aiken)

Lutz, N.W., Tome, M.E., Aiken, N.R. and Briehl, M.M.   Changes in phosphate metabolism in thymoma cells

suggest mechanisms for resistance to dexamethasone-induced apoptosis.  A 31P NMR spectroscopic study

of cell extracts.  NMR Biomed, 15:  356-366, 2002.

Grant, S., Aiken, N.R., Plant, D., Gibbs, S., Moreci, T.H., Webb, A. and Blackband, S.J.  Spatially localized NMR spectroscopy of single neurons. (in press)

Ting, Y-L., Zhao, M., Gillies, R.J. and Aiken, N.R.  Phosphomonoester metabolism as a function of growth in

human breast cancer cells:  MRS analyses. (submitted, Magn. Reson. Med.)

Aiken, N.R. and Van Sluis, R.  “31P Magnetic Resonance Spectroscopy and Phospholipid Metabolism” in

Essential Elements of MRI and MRS, CRC Press (in press).

Hsu, E.W., Aiken, N.R. and Blackband, S.J.  A Study of Diffusion Isotropy in Single Neurons by Using NMR

Microscopy.  Magn. Reson. Med. 37: 624-627, 1997.

Aiken, N.R., Hsu, E.W. and Blackband, S.J.  Maturation Effects on the NMR Characteristics in Microimaging of

Single Neurons.  Am. J. Physiol.  271 (Cell Physiol. 40):  C1295-C1302, 1996.

Aiken, N.R., Szwergold, B.S., Kappler, F., Stoyanova, R., Kuesel, A.C., Shaller, C. and Brown, T.R.  Metabolism

of Phosphonium Choline by Rat-2 Fibroblasts:  Effects of Mitogenic Stimulation Studied Using 31P NMR

Spectroscopy.  Anticancer Res. 16:  1357-1364, 1996.

Kuesel, A.C., Stoyanova, R., Aiken, N.R., Szwergold, B., Shaller, C. and Brown, T.R.  Potential and Limitations

of Quantitation of Peaks in Biological 31P NMR Spectra via Principal Component Analysis.  NMR Biomed 9: 

93-104, 1996.

Aiken, N.R., Hsu, E.W. and Blackband, S.J.  A Review of NMR Microimaging of Single Cells.  J. Magn. Reson.

Anal. 1:  41-48, 1995.

Hsu, E.W., Schoeniger, J.S.,  Bowtell, R., Aiken, N.R., Horsman, A. and Blackband, S.J.  A Modified Imaging

Sequence for Accurate T2  Measurements Using NMR Microscopy.  J. Magn. Reson.  B 109:  66-69, 1995.

Bowtell, R., Peters, A., Sharp, J.C., Mansfield, P., Hsu, E., Aiken, N., Horsman, A. and Blackband, S.J.  NMR

Microscopy of Single Neurons at 500 MHz Using Spin-Echo and Line-Narrowed 2DFT Imaging.  Magn. Reson.

Med.  33:  790-794, 1995.

Aiken, N. R., Galey, W.R. & Satterlee, J.D.  A Peroxidative Model of Human Erythrocyte Intracellular Ca2+

Changes with in vivo Cell Aging:  Measurement by 19F NMR Spectroscopy.  Biophys. Biochim. Acta 1270: 

52-57, 1995.

Blackband, S.J., Bowtell, R., Peters, A., Sharp, J.C., Mansfield, P., Hsu, E., Horsman, A. and Aiken, N.R. 

NMR Microscopy of Single Neurons at 500 MHz.  MAGMA 2:  445-447, 1994.

Aiken, N.R., McGovern, K.G., Ng, C.E., Wehrle, J.P. and Glickson, J.D.  31P NMR Spectroscopic Studies of the

Effects of Cyclophosphamide on Perfused RIF-1 Tumor Cells.  J. Magn. Reson. Med. 31: 241-247, 1994.

Schoeniger, J.S., Aiken, N., Hsu, E. and Blackband, S.J.  Relaxation-Time and Diffusion NMR Microscopy of

Single Neurons.  J. Magn. Reson. B 103: 261-273, 1994.

Aiken, N.R., Galey, W.R. & Satterlee, J.D.  19F NMR Measurement of Intracellular Ca2+ Changes in the Aging

Human Erythrocyte.  Biophys. Biochim. Acta 1136: 155-160, 1992.

Ph.D. Dissertation:  Human Red Cell Intracellular Calcium Changes Induced by Aging and a Peroxidative

Model of Aging, Studied Using 19F Nuclear Magnetic Resonance.  University of New Mexico, Albuquerque,

NM, 1990.

Master's Thesis:  The Effect of Chromium and Glucose Tolerance Factor (GTF) on Insulin Activity in Diabetic

and Normal Animals.  NMIMT, Socorro, NM, 1984.

ABSTRACTS

Aiken, N.R., Ting, Y-L.T., Zhao, M. and Gillies, R.J.  Phosphoethanolamine Metabolism in Human Breast

Cancer Cells:  studied using 31P, 13C MRS and 3H-Radiotracers. Proceed. Internat. Soc. Magn. Reson. Med., 6, 615, 1998.

Ting, Y-L.T., Zhao, M., Galons, J.P., Aiken, N.R. and Gillies, R.J.  31P MRS Studies of Phosphomonoester

Metabolism in Human Breast Cancer Cells:  Tumorogenicity and Growth Status. Proceed. Internat. Soc.

Magn. Reson. Med., 5: 1103, 1997.

Hsu, E., Aiken, N. And Blackband, S. (Sponsor:  J. Forder)  Cellular Basis for the Decrease of Tissue Water

Diffusion in Acute Brain Ischemia Determined by NMR Microscopy.  Exp. Biol., 1996.

Hsu, Edward W., Aiken, Nanci R., Blackband and Stephen J.  NMR Microscopy Demonstrates an Isotropic

Apparent Diffusion Coefficient of Water in Single Neurons.  Proceed. Internat. Soc. Magn. Reson. Med., 4: 260, 1996.

Szwergold, B.S., Shaller, C., Kappler, F., Aiken, N.R., Stoyanova, R. and Brown, T.R.  Effects of mitogenic

stimulation on choline and phosphatidylcholine metabolism in mammalian cells.  Proceed. Internat. Soc.

Magn. Reson. Med., 4: 268, 1996.

Hsu, Edward W., Aiken, Nanci R. and Blackband, Stephen J.  Cellular Basis for the Decrease of Tissue Water

Diffusion in Acute Brain Ischemia.  Proceed. Internat. Soc. Magn. Reson. Med., 4: 313, 1996.

Raghunand, N., Aiken, N.R., Bhujwalla, Z.M. and Gillies, R.J.  Measurement of Extracellular pH in vivo Using

3-aminopropylphosphonate:  Deconvolution of T2* Effects.  Proceed. Internat. Soc. Magn. Reson. Med., 4: 111, 1996.

Ting, Y-L.T., Aiken, N.R., Myers, D., Weibel, J. and Gillies, R.J.  Phospholipid Metabolism in Human Breast

Epithelial Cell Lines as a Function of Oncogenic Transformation and Growth Status:  31P & 13C NMR Studies. 

Proceed. Internat. Soc. Magn. Reson. Med., 4: 1142, 1996.

Trouard, T.P., Aiken, N.R. and McGovern, K.A.  Correlation of Extracellular Volume Fraction and Apparent

Diffusion Coefficient in Red Blood Cell Suspensions via DWI and 31P MRS.   Proceed. Internat. Soc. Magn. Reson.  Med., 4: 1331, 1996.

Hsu, E., Schoeniger, J., Aiken, N. and Blackband, S.  Accurate T2 Measurements using a Modified NMR

Microimaging Sequence.  Proceed. Soc. Magn. Reson., 3: 1181, 1995.

Hsu, E., Schoeniger, J., Bowtell, R., Aiken, N., Horsman, A. and Blackband, S.  A Modified Microimaging

Sequence for Accurate T2 Measurements.  36th Experimental NMR Conference, Boston, March 1995.

Aiken, N.R., Hsu, E. W., Blackband, S.J. and Horsman, A.  Maturation Effects on the NMR Characteristics in

 Microscopy of Single Neurons. Proceed. Soc. Magn. Reson., 2: 711, 1994.

Hsu, E. W., Aiken, N.R., and Blackband, S.J.  NMR Microimaging of Perfused Single Cells. Proceed. Soc. Magn. Reson., 2: 717, 1994.

Hsu, E. W., Aiken, N.R.,  and Blackband, S.J.  A Simplified Magnetization Transfer Analysis Using T1sat.

Proceed. Soc. Magn. Reson., 2: 874, 1994.

Blackband, S.J., Bowtell, R., Peters, A., Sharp, J.C., Mansfield, P., Hsu, E., Aiken, N., Horsman, A.  NMR

Microscopy of Single Neurons at 500 MHz.  1st Nottingham Symposium on Magnetic Resonance in Medicine,

Nottingham, England, April, 1994.

Aiken, N.R., Szwergold, B.S., Kappler, F., Shaller, C. and Brown, T.J.  Incorporation of Phosphonium Choline

into Membranes.  Fogarty International Conference on Domain Organization in Biological Membranes,

Washington, D.C., March, 1994.

Blackband, S.J., Hsu, E., Aiken, N., Schoeniger, J.S.  NMR Microscopy of Single Neurons:  the Properties of

Cellular Water.  BIR Radiology and Oncology '93, Glasgow, Scotland, 1993; Brit. J. Radiol. 66, S117, 1993.

Bowtell, R., Peters, A., Sharp, J., Mansfield, P., Aiken, N., Hsu, E., Horsman, A. and Blackband, S.  NMR

Microscopy of Single Neurons at 500 MHz Using Spin Echo and Line-Narrowed 2DFT Imaging.    Proceed.

Soc. Magn. Reson. Med., 12: 936, 1993.

Aiken, N.R., Shungu, D., Werhle, J.P. and Glickson, J.D.  Metabolic Differences Between Two EMT6 Tumor

Sublines:  in vivo and in vitro  1H and 31P Studies. Proceed. Soc. Magn. Reson. Med., 11: 169,1992.

Hsu, E.W., Aiken, N.R., Schoeniger, J.S. and Blackband, S.J.  Magnetization Transfer Microimaging of Single

Neurons. Proceed. Soc. Magn. Reson. Med., 11: 974,1992.

Chance, E.M., Chatham, J.C., Forder, J.R., Aiken, N.R., Werhle, J.P. and Glickson, J.D.  Calculation of absolute

Metabolic Fluxes Through Both Glycolytic and Oxidative Pathways:  Analyzing 13C NMR Kinetic Data by

Non-Linear Least Squares Methods. Proceed. Soc. Magn. Reson. Med., 11: 3828,1992.

Shungu, D.C., Bhujwalla, Z.M., Aiken, N.R., Wehrle, J.P. and Glickson, J.D.  Assignment of Resonances in

the 1H NMR Spectrum of Subcutaneous EMT6/SF Mammary Adenocarcinoma Tumors by 2D COSY

Analysis of Tissue Extracts. Proceed. Soc. Magn. Reson. Med., 11: 3537,1992.

Shungu, D.C., Bhujwalla, Z.M., Aiken, N.R., Wehrle, J.P. and J.D. Glickson.  1H Magnetic Resonance

Spectroscopy of Subcutaneous Tumors in Mice:  Effects of Growth, Chemotherapy and Blood Flow Reduction. 

XV International Conference on Magnetic Resonance in Biological Systems, Jerusalem, Israel, 1992.

Schoeniger, J.S., Aiken, N. and Blackband, S.J.  NMR Microscopy of Single Neurons.  ESMRMB, Zurich, 1991.

Schoeniger, J.S., Aiken, N., Blackband, S.J.  Relaxation Time and Diffusion NMR Microscopy on Single

Neurons.  International Conference on Microscopy, Heidelberg, Germany, 1991.

Blackband, S.J., Schoeniger, J.S., Aiken, N. and Hsu, E.  NMR Microscopy and Its Application to Single

Neurons.  Ann. Mtg. of the Washington, D.C. Area NMR Group, NIH, Bethesda, MD, 1991.

Aiken, N.R., Galey, W.R. and Satterlee, J.D.  19F NMR Measurement of Intracellular Ca2+ in Old and Young

Human Erythrocytes.  Biophys. J. 57: 94a. 1990.

Aiken, N.R., Galey, W.R. and Satterlee, J.D.  Peroxidative Stress Increases  Intracellular Ca2+ of Young Human

Erythrocytes, as Measured by 19F NMR.  10th International Biophysics Congress, Vancouver, Canada.  1990.

Aiken, N.R., Galey, W.R. and Satterlee, J.D.  Anion Exchange in Young and Old  Human Red Blood Cells

Using 35Cl NMR.  UNM School of Medicine, Graduate Student Research Presentation.  1989.

Aiken, N.R., Satterlee, J.D. and Galey, W.R.  Kinetics of Chloride-Sulfate Exchange in Young and Old Human

Red Blood Cells using 35Cl NMR.  Symposium on Oxygen Binding Heme Proteins:  Structure, Dynamics,

Function & Genetics.  Asilomar, CA.  1988

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